The Usage of Tocolytic Drugs in Pregnant Women With the Threat or Preterm Labor in PKU Muhhamadiyah Gamping Hospital Yogyakarta

Abstract

Partus Prematurus Imminens (PPI) is a threat to pregnancy caused by contractions in the uterus at a gestational age that has not reached 37 weeks, or what is commonly called preterm labour. According to the WHO, there are around 10-11% of preterm births in the world each year, while in Indonesia, the WHO explains that there are around 16% of preterm deliveries, which places Indonesia in fifth place with the largest preterm deliveries in the world. Management and prevention efforts with tocolytic therapy is a therapy used to suppress uterine contractions. This research used analytic descriptive observational with a cross-sectional approach where these observations were made within the past 5 years. The sample in this study was conducted on pregnant women who experienced the threat of preterm labour. This research found that most of the samples recovered as many as 23 (95.8%) people, and the most used drug was Nifedipine, with a recovery status of 12 (50.0%) people, while the rest were Hystolan. However, there was no significant relationship between drug use and recovery in pregnant women with imminent premature labour, as shown by the Fisher Exact Test, p value> 0.05. Tocolytic drugs are effective to be given to pregnant women with Partus Prematurus Imminens (PPI). However, there was no significant relationship between the drug (Nifedipine and Hystolan) and the recovery of pregnant women with imminent preterm labour (PPI) at PKU Muhammadiyah Gamping Hospital, Yogyakarta.